Detalhe da pesquisa
1.
Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation.
Proc Natl Acad Sci U S A
; 121(18): e2202003121, 2024 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38669184
2.
The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder.
Trends Immunol
; 43(8): 630-639, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35840529
3.
Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.
PLoS Pathog
; 18(7): e1010110, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35797416
4.
Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.
PLoS Pathog
; 17(9): e1009581, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34529720
5.
Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.
Nucleic Acids Res
; 42(8): 4996-5006, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24589584
6.
Genomic profiling of HIV-1 integration in microglia cells links viral integration to the topologically associated domains.
Cell Rep
; 42(2): 112110, 2023 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36790927
7.
Single cell multiomic analysis reveals diabetes-associated ß-cell heterogeneity driven by HNF1A.
Nat Commun
; 14(1): 5400, 2023 09 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37669939
8.
CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor.
J Biol Chem
; 286(46): 40083-90, 2011 Nov 18.
Artigo
Inglês
| MEDLINE | ID: mdl-21953454
9.
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
Nat Cell Biol
; 5(4): 320-9, 2003 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-12652308
10.
Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress.
EMBO Mol Med
; 13(8): e13901, 2021 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34289240
11.
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.
Nat Metab
; 2(12): 1443-1458, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33257854
12.
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation.
Oncogene
; 22(37): 5813-27, 2003 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12947388
13.
IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects.
Mutat Res
; 568(1): 97-110, 2004 Dec 02.
Artigo
Inglês
| MEDLINE | ID: mdl-15530543
14.
Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.
PLoS One
; 8(11): e81154, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24260551
15.
Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO.
Cancer Biol Ther
; 7(5): 709-17, 2008 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18277094
16.
Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro.
Int J Nanomedicine
; 1(2): 155-62, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-17722531
17.
Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor.
J Biol Chem
; 280(14): 14212-21, 2005 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-15689620
18.
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
J Biol Chem
; 278(13): 11590-600, 2003 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-12551933